Randomized clinical studies of the effectiveness of garlic (Allium sativum), ginkgo biloba (Ginkgo biloba), hawthorn (Crataegus), pycnogenol, or Pinto martima bark extract, Oea leaf extract (Oea) have been used in arterial hypertension (AH), garlic (Allium sativum). , Asian ginseng root (ginseng wounds), coenzyme Q10, calcium and magnesium.
The results vary, and the effect is usually small. In a meta-analysis, it was shown that, compared with placebo, the use of garlic leads to a decrease in CAD, an average of 8 mm Hg. Art., and dad – 5 mm Hg. However, in a systematic review of 27 small, randomized, placebo-controlled studies of short duration, in 26 of which only adult patients participated, mixed, but always small effects of different garlic-based drugs in relation to blood pressure were obtained.
Most studies did not reveal significant differences in blood pressure levels in patients randomly assigned to the garlic group compared with the placebo group. The undesirable effects of oral intake of garlic included bad breath and body odor.
Other possible, but unproven, adverse events included flatulence, pain in the esophagus and abdomen, small bowel obstruction, contact dermatitis, rhinitis, asthma, bleeding, and MI.
In a systematic review of the use of coenzyme Q10 in arterial hypertension (AH) in 8 studies showed an average decrease in the GARDEN by 16 mm Hg. Art. and DBP – at 10 mm Hg. however, only 50% of the studies were placebo-controlled. The latest Cochrane review confirmed the ineffectiveness of the combined dietary supplement containing calcium, magnesium and potassium in terms of treating primary hypertension in adults.